Screening for Beta-Lactamases Producing Bacteria and Other Resistant Bacteria among Patients Admitted to the Emergency Unit at the Yaoundé University Teaching Hospital, Cameroon

Aims: This study aimed to screen for Beta Lactamases (BLs) and other resistant bacteria among patients admitted the emergency unit of Yaoundé University Teaching Hospital (YUTH).
 Study Design: was a cross-sectional hospital-based study.
 Place Duration Study: conducted at Bacteriology YUTH, Yaoundé- Cameroon between February June 2020.
 Methodology: Seventy-Five urine samples were collected from newly YUTH species identified basis on their culture characteristics, Gram morphology, biochemical tests. The isolates screened production extended-spectrum beta-lactamases (ESBLs) AmpC BLs using Double disk synergy method Disk approximation methods respectively. These later subjected antimicrobial susceptibility testing diffusion method.
 Results: Out 75 analyzed, 14 (18.7%) found positive Urinary Tract Infection. Fourteen isolated enumerated as E. coli (5), Klebsiella (4), Citrobacter (2), Proteus Enterobacter (1). A high level resistance observed with Amoxicillin clavulanic acid, Cefuroxime, Ceftazidime while sensitivity carbapenem antibiotics. Eight producers, which 5 sorely ESBL 2 co-producers (ESBL + AmpC), 1 producer. overall rate in population 10.7%. Again, patient origin previous antibiotic use significantly associated prevalence p-value .01 .04 respectively.
 Conclusion: ß- lactamases Emergency emphasizes need continuous surveillance detect strains, strict guidelines therapy, implementation infection control measures reduce increasing burden resistance.